Gene functional similarity search tool

2019-09-21 02:12

ADaGOFun is a repository of python modules for analyzing protein or gene sets at the functional level based on GO annotations using information contentbased SS measures. It contains six main functions and implements 101 different functional similarity measures (see Supplementary File).Search by GO terms GFSST provides a robust retrieval tool for gene and gene products based on their associated GO terms. For example, glucose metabolism is a critical pathway in the study of diabetes. DNA damage response, signal transduction by P53 class mediator (GO: ) is a very important gene functional similarity search tool

In recent years, the development of Gene Ontology (GO) has established structured, controlled vocabularies describing gene functions, which makes it possible to develop novel tools to search genes by functional similarity.

Gene functional similarity search tool free

In recent years, the development of Gene Ontology (GO) has established structured, controlled vocabularies describing gene functions, which makes it possible to develop novel tools to search genes by functional similarity. By using a statistical model to measure the functional similarity of genes based on the Gene Ontology directed acyclic graph, we developed a novel Gene Functional Similarity Search Tool (GFSST) togene functional similarity search tool GFSST is a search engine that lets users design their search targets by gene functions. It provides functions not only for similar gene retrieval but also for gene search by one or more Gene Ontology

For example, GOTax provides a functional similarity search tool for a group of proteins and protein families, with their GO annotations as input. GSESAME [ 14 is an online tool for measuring the semantic similarity between two genes. gene functional similarity search tool In recent years, the development of Gene Ontology (GO) has established structured, controlled vocabularies describing gene functions, which makes it possible to develop novel tools to search genes by functional similarity. Results By using a statistical model to measure the functional similarity of genes based on the Gene Ontology The Functional Classification Tool generates a genetogene similarity matrix based shared functional annotation using over 75, 000 terms from 14 functional annotation sources. Our novel clustering algorithms classifies highly related genes into functionally related groups. For example, GOTax [13 provides a functional similarity search tool for a group of proteins and protein families, with their GO annotations as input. GSESAME [14 is an online tool for measuring the semantic similarity between two genes. In recent years, the development of Gene Ontology (GO) has established structured, controlled vocabularies describing gene functions, which makes it possible to develop novel tools to search genes by functional similarity.

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